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CHAPTER 4: DECISION-MAKING IN ADHD FROM NEUROSCIENCES PERSPECTIVES


The decision-making process involves several crucial steps that comprise problem recognition, data collection, option analysis, weighing pros and cons, selection of the best course of action, execution, and result evaluation. Making effective decisions involves analyzing different factors using either rational or intuitive approaches, depending on the complexity of the situation and one’s cognitive processes. Rational decision-making entails analyzing all available information, while intuitive decision-making relies on gut feelings and past experiences. Understanding and assessing decision-making from a developmental standpoint is crucial. This is especially true for understanding children’s cognitive abilities at different ages.


Children’s risk preferences, for instance, may vary depending on social and economic factors, with education level a predictor of cognitive and academic abilities. Research on children’s decision-making in risky situations involves selecting options with varying potential outcomes and probabilities. Distinguishing between random and non-random outcomes is essential for accurate risk estimation, a skill even children as young as four can show. However, adolescents with ADHD may be particularly vulnerable in decision-making, necessitating vigilance against common pitfalls such as hasty judgments and disregarding conflicting evidence.


Furthermore, behavioral economic approaches consider individuals to be active decision-makers who choose based on the expected value of the alternatives. In the normative expected utility framework, for example, individuals determine the expected value of a risky alternative by weighting its subjective potential payoff by probability. Rational decision-makers choose the option with the highest expected value. Their risk attitude influences their choice and this ranges from risk aversion to risk-seeking. Research shows that people with ADHD may not seek risks, yet, they see the outcomes of risky behaviors as especially appealing or less dangerous.


Besides, children with ADHD often underestimate the consequences of risky activities and overestimate their physical abilities while neglecting negative consequences. Adolescents with ADHD, in addition, may have lesser negative expectations of the outcomes of risky behaviors, which can lead to poor decision-making. These findings match with the concept of a “positive illusion” where studies investigating functional connectivity within the Default Mode Network (DMN) reveal alterations in individuals with ADHD.


Meanwhile, the relationship between ADHD and economic behaviors is regarded to be complex and diverse. Individuals with ADHD, in some cases, may exhibit impulsive spending, risk-taking, time management, and planning challenges, workplace difficulties, and financial aspects of treatment. Understanding these dynamics is crucial for developing tailored interventions and support for therapeutic approaches and broader financial planning and well-being. Managing ADHD often requires therapeutic interventions, medications, and support, which can have an economic impact. By studying an individual’s environment, researchers can gain insights into the decision-making abilities of those with ADHD.


Finally, people with ADHD tend to engage in suboptimal decision-making. Individuals with ADHD, for example, often exhibit structural deviations in their brains as evidenced by studies using high-resolution fMRI and PET scans. These deviations include hypoactivity in the Prefrontal Cortex (PFC), which plays a crucial role in executive functions, and altered activation patterns in the Striatum, central to reward processing. PET studies have also revealed decreased dopamine receptor availability and transporter density in the brains of individuals with ADHD. As these anomalies underlie the impulsive and reward-seeking behaviors typical of ADHD, studies using Event-Related Potentials (ERPs) have shown that individuals with ADHD often exhibit atypical waveforms; suggesting disruptions in attentional processing and subsequent decision-making paradigms.


Resting-state fMRI studies, for instance, have highlighted disrupted functional connectivity patterns in ADHD, particularly between the PFC and other essential decision-making regions. A nuanced understanding of ADHD’s neural architecture can refine therapeutic modalities like Cognitive Behavioral Therapy (CBT) and real-time neural data where they can be utilized to develop neurofeedback interventions along with a detailed understanding of the implicated neural pathways and neurotransmitter systems, which can guide the development of pharmacological interventions.

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